CLK2 抗体 (N-Term)
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- 抗原 See all CLK2 抗体
- CLK2 (CDC-Like Kinase 2 (CLK2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CLK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- CLK2 Antibody detects endogenous levels of total CLK2.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CLK2, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
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anti-CDC-Like Kinase 2 (CLK2) (N-Term) antibody
CLK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CDC-Like Kinase 2 (CLK2) (AA 240-499) antibodyCLK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CDC-Like Kinase 2 (CLK2) (N-Term) antibodyCLK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CDC-Like Kinase 2 (CLK2) (AA 1-498) antibodyCLK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CDC-Like Kinase 2 (CLK2) (AA 66-93), (N-Term) antibodyCLK2 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-CDC-Like Kinase 2 (CLK2) (AA 239-498) antibodyCLK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CDC-Like Kinase 2 (CLK2) (AA 1-30), (N-Term) antibodyCLK2 适用: 人 WB 宿主: 兔 Polyclonal RB3205 unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CLK2 (CDC-Like Kinase 2 (CLK2))
- 别名
- CLK2 (CLK2 产品)
- 别名
- MGC53993 antibody, hclk2 antibody, clk2 antibody, fb20c02 antibody, si:ch211-81a5.7 antibody, wu:fb20c02 antibody, MGC131228 antibody, hCLK2 antibody, AU041688 antibody, Tu52 antibody, CDC like kinase 2 antibody, CDC like kinase 2 S homeolog antibody, CDC-like kinase 2a antibody, CDC like kinase 2 L homeolog antibody, CDC-like kinase 2 antibody, CLK2 antibody, clk2.S antibody, clk2 antibody, clk2a antibody, clk2.L antibody, Clk2 antibody
- 背景
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Description: Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Acts as a suppressor of hepatic gluconeogenesis and glucose output by repressing PPARGC1A transcriptional activity on gluconeogenic genes via its phosphorylation. Phosphorylates PPP2R5B thereby stimulating the assembly of PP2A phosphatase with the PPP2R5B-AKT1 complex leading to dephosphorylation of AKT1. Phosphorylates: PTPN1, SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.
Gene: CLK2
- 分子量
- 60 kDa
- 基因ID
- 1196
- UniProt
- P49760
- 途径
- Regulation of Carbohydrate Metabolic Process
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