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CREB3L2 抗体 (Internal Region)

CREB3L2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257984
发货至: 中国
  • 抗原 See all CREB3L2 抗体
    CREB3L2 (CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2))
    抗原表位
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 32
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 29
    • 2
    • 2
    克隆类型
    • 31
    • 2
    多克隆
    标记
    • 17
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CREB3L2 antibody is un-conjugated
    应用范围
    • 26
    • 21
    • 5
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    CREB3L2 Antibody detects endogenous levels of total CREB3L2.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CREB3L2, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CREB3L2 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    CREB3L2 (CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2))
    别名
    CREB3L2 (CREB3L2 产品)
    别名
    CREB3L2 antibody, bbf2h7 antibody, BBF2H7 antibody, C530025K05Rik antibody, Ra69 antibody, SCIRR69 antibody, zgc:158603 antibody, cAMP responsive element binding protein 3 like 2 antibody, cAMP responsive element binding protein 3-like 2 antibody, cAMP responsive element binding protein 3-like 2 L homeolog antibody, CREB3L2 antibody, creb3l2 antibody, Creb3l2 antibody, creb3l2.L antibody
    背景

    Description: Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis by activating the transcription of SEC23A, which promotes the transport and secretion of cartilage matrix proteins, and possibly that of ER biogenesis-related genes (By similarity). In a neuroblastoma cell line, protects cells from ER stress-induced death (PubMed:17178827). In vitro activates transcription of target genes via direct binding to the CRE site (PubMed:17178827).

    Gene: CREB3L2

    分子量
    58 kDa
    基因ID
    64764
    UniProt
    Q70SY1
    途径
    Thyroid Hormone Synthesis
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