BCOR 抗体 (Internal Region)
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- 抗原 See all BCOR 抗体
- BCOR (BCL6 Co-Repressor (BCOR))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BCOR antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- BCOR Antibody detects endogenous levels of total BCOR.
- 预测反应
- Pig,Bovine,Sheep,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human BCOR, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product BCOR Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- BCOR (BCL6 Co-Repressor (BCOR))
- 别名
- BCOR (BCOR 产品)
- 别名
- ANOP2 antibody, MAA2 antibody, MCOPS2 antibody, BCOR antibody, RGD1562735 antibody, 5830466J11Rik antibody, 8430401K06Rik antibody, BcorR antibody, D930024N20Rik antibody, mKIAA1575 antibody, BCL6 corepressor antibody, BCL6 co-repressor antibody, BCL6 interacting corepressor antibody, BCOR antibody, bcor antibody, Bcor antibody
- 背景
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Description: Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A, impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells, the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).
Gene: BCOR
- 分子量
- 192 kDa
- 基因ID
- 54880
- UniProt
- Q6W2J9
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