BAI1 抗体 (Internal Region)
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- 抗原 See all BAI1 抗体
- BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BAI1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- BAI1 Antibody detects endogenous levels of total BAI1.
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human BAI1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product BAI1 Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
- 别名
- BAI1 (BAI1 产品)
- 别名
- BAI1 antibody, GDAIF antibody, B830018M07Rik antibody, R75078 antibody, mKIAA4089 antibody, brain-specific angiogenesis inhibitor 1 antibody, adhesion G protein-coupled receptor B1 antibody, BAI1 antibody, ADGRB1 antibody, LOC100228084 antibody, Adgrb1 antibody
- 背景
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Description: Phosphatidylserine receptor which enhances the engulfment of apoptotic cells (PubMed:24509909). Also mediates the binding and engulfment of Gram-negative bacteria (PubMed:26838550). Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity (PubMed:26838550). In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells (PubMed:24509909). Promotes myoblast fusion (By similarity). Activates the Rho pathway in a G-protein-dependent manner (PubMed:23782696). Inhibits MDM2-mediated ubiquitination and degradation of DLG4/PSD95, promoting DLG4 stability and regulating synaptic plasticity (By similarity). Required for the formation of dendritic spines by ensuring the correct localization of PARD3 and TIAM1 (By similarity). Potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53/TP53 signal in suppression of glioblastoma (PubMed:11875720).
Gene: BAI1
- 分子量
- 174 kDa
- 基因ID
- 575
- UniProt
- O14514
- 途径
- p53 Pathway
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