ARFGAP1 抗体 (Internal Region)
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- 抗原 See all ARFGAP1 抗体
- ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARFGAP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- ARFGAP1 Antibody detects endogenous levels of total ARFGAP1.
- 预测反应
- Rabbit
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ARFGAP1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ARFGAP1 Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))
- 别名
- ARFGAP1 (ARFGAP1 产品)
- 别名
- ARF1GAP antibody, HRIHFB2281 antibody, AI115377 antibody, Arf1gap antibody, Arf GAP1 antibody, arf1gap antibody, atfb1 antibody, atfb3 antibody, jlns1 antibody, k(v)7.1 antibody, kcna8 antibody, kcna9 antibody, kv1.9 antibody, kv7.1 antibody, kvlqt1 antibody, lqt antibody, lqt1 antibody, rws antibody, sqt2 antibody, wrs antibody, ARFGAP3 antibody, ADP ribosylation factor GTPase activating protein 1 antibody, ADP-ribosylation factor GTPase activating protein 1 antibody, ADP ribosylation factor GTPase activating protein 1 S homeolog antibody, putative ADP-ribosylation factor GTPase activating protein 1 antibody, ATP-dependent RNA helicase DBP9 antibody, ARFGAP1 antibody, Arfgap1 antibody, arfgap1.S antibody, Tb11.01.6060 antibody, arfgap1 antibody, LMJF_32_1230 antibody, MGYG_02419 antibody
- 背景
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Description: GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine (By similarity).
Gene: ARFGAP1
- 分子量
- 60/48 kDa
- 基因ID
- 55738
- UniProt
- Q8N6T3
- 途径
- p53 Pathway, ER-Nucleus Signaling, Unfolded Protein Response
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