ARHGAP18 抗体 (Internal Region)
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- 抗原 See all ARHGAP18 抗体
- ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))
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抗原表位
- Internal Region
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARHGAP18 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- RHG18 Antibody detects endogenous levels of total RHG18.
- 预测反应
- Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human RHG18, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ARHGAP18 Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))
- 别名
- ARHGAP18 (ARHGAP18 产品)
- 别名
- 4833419J07Rik antibody, AI314906 antibody, AI843501 antibody, MacGAP antibody, SENEX antibody, bA307O14.2 antibody, MGC146282 antibody, DKFZp469I1011 antibody, Rho GTPase activating protein 18 antibody, Rho GTPase activating protein 18 L homeolog antibody, Arhgap18 antibody, ARHGAP18 antibody, arhgap18 antibody, arhgap18.L antibody
- 背景
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Description: Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702). Regulates cell shape, spreading, and migration (PubMed:21865595).
Gene: ARHGAP18
- 分子量
- 75 kDa
- 基因ID
- 93663
- UniProt
- Q8N392
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