TRIO 抗体 (Internal Region)
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- 抗原 See all TRIO 抗体
- TRIO (Triple Functional Domain Protein (TRIO))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRIO antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- TRIO Antibody detects endogenous levels of total TRIO.
- 预测反应
- Pig,Zebrafish,Horse,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human TRIO, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product TRIO Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- TRIO (Triple Functional Domain Protein (TRIO))
- 别名
- TRIO (TRIO 产品)
- 别名
- ARHGEF23 antibody, tgat antibody, 6720464I07Rik antibody, AA408740 antibody, Solo antibody, si:dz230d15.1 antibody, trio Rho guanine nucleotide exchange factor antibody, triple functional domain (PTPRF interacting) antibody, trio Rho guanine nucleotide exchange factor b antibody, TRIO antibody, Trio antibody, triob antibody
- 背景
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Description: Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases (PubMed:8643598, PubMed:27418539). Involved in coordinating actin remodeling, which is necessary for cell migration and growth (PubMed:10341202). In developing hippocampal neurons, limits dendrite formation, without affecting the establishment of axon polarity. Once dendrites are formed, involved in the control of synaptic function by regulating the endocytosis of AMPA-selective glutamate receptors (AMPARs) at CA1 excitatory synapses (By similarity). May act as a regulator of adipogenesis (By similarity).
Gene: TRIO
- 分子量
- 31 kDa
- 基因ID
- 7204
- UniProt
- O75962
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