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DOCK1 抗体 (C-Term)

DOCK1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257863
发货至: 中国
  • 抗原 See all DOCK1 抗体
    DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
    抗原表位
    • 15
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 30
    • 22
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 42
    • 1
    • 1
    • 1
    克隆类型
    • 44
    • 1
    多克隆
    标记
    • 18
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DOCK1 antibody is un-conjugated
    应用范围
    • 15
    • 13
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    DOCK1 Antibody detects endogenous levels of total DOCK1.
    预测反应
    Zebrafish,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human DOCK1, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product DOCK1 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
    别名
    DOCK1 (DOCK1 产品)
    别名
    DOCK180 antibody, ced5 antibody, 9130006G06Rik antibody, AI854900 antibody, D630004B07Rik antibody, RGD1566072 antibody, dedicator of cytokinesis 1 antibody, dedicator of cytokinesis protein 1 antibody, dedicator of cyto-kinesis 1 antibody, DOCK1 antibody, Dock1 antibody, dock1 antibody, CpipJ_CPIJ002759 antibody
    背景

    Description: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829). Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed:8657152).

    Gene: DOCK1

    分子量
    215 kDa
    基因ID
    1793
    UniProt
    Q14185
    途径
    Signaling of Hepatocyte Growth Factor Receptor
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