DOCK1 抗体 (C-Term)
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- 抗原 See all DOCK1 抗体
- DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DOCK1 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- DOCK1 Antibody detects endogenous levels of total DOCK1.
- 预测反应
- Zebrafish,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human DOCK1, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product DOCK1 Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
- 别名
- DOCK1 (DOCK1 产品)
- 别名
- DOCK180 antibody, ced5 antibody, 9130006G06Rik antibody, AI854900 antibody, D630004B07Rik antibody, RGD1566072 antibody, dedicator of cytokinesis 1 antibody, dedicator of cytokinesis protein 1 antibody, dedicator of cyto-kinesis 1 antibody, DOCK1 antibody, Dock1 antibody, dock1 antibody, CpipJ_CPIJ002759 antibody
- 背景
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Description: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829). Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed:8657152).
Gene: DOCK1
- 分子量
- 215 kDa
- 基因ID
- 1793
- UniProt
- Q14185
- 途径
- Signaling of Hepatocyte Growth Factor Receptor
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