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- 抗原 See all ACER2 抗体
- ACER2 (Alkaline Ceramidase 2 (ACER2))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ACER2 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- ASAH3L Antibody detects endogenous levels of total ASAH3L
- 交叉反应
- 人, 小鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide
- 亚型
- IgG
- Top Product
- Discover our top product ACER2 Primary Antibody
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anti-Alkaline Ceramidase 2 (ACER2) (Internal Region) antibody
ACER2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Alkaline Ceramidase 2 (ACER2) antibodyACER2 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Alkaline Ceramidase 2 (ACER2) antibodyACER2 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Alkaline Ceramidase 2 (ACER2) (Middle Region) antibodyACER2 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500~1:1000, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- ACER2 (Alkaline Ceramidase 2 (ACER2))
- 别名
- ASAH3L (ACER2 产品)
- 别名
- ASAH3L antibody, asah3l antibody, ALKCDase2 antibody, 2410116I05Rik antibody, Asah3l antibody, CRG-L1 antibody, maCER2 antibody, alkaline ceramidase 2 antibody, alkaline ceramidase 2 S homeolog antibody, ACER2 antibody, acer2.S antibody, acer2 antibody, Acer2 antibody
- 背景
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Description: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. Unsaturated long-chain ceramides are the best substrates, saturated long-chain ceramides and unsaturated very long-chain ceramides are good substrates, whereas saturated very long-chain ceramides and short-chain ceramides were poor substrates. The substrate preference is D-erythro-C(18:1)-, C(20:1)-, C(20:4)-ceramide > D-erythro-C(16:0)-, C(18:0), C(20:0)-ceramide > D-erythro-C(24:1)-ceramide > D-erythro-C(12:0)-ceramide, D-erythro-C(14:0)-ceramides > D-erythro-C(24:0)-ceramide > D-erythro-C(6:0)-ceramide. Inhibits the maturation of protein glycosylation in the Golgi complex, including that of integrin beta-1 (ITGB1) and of LAMP1, by increasing the levels of sphingosine. Inhibits cell adhesion by reducing the level of ITGB1 in the cell surface. May have a role in cell proliferation and apoptosis that seems to depend on the balance between sphingosine and sphingosine-1-phosphate.
Gene: ACER2
- 分子量
- 33 kDa
- 基因ID
- 340485
- UniProt
- Q5QJU3
- 途径
- Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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