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MED1 抗体 (C-Term)

MED1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257759
发货至: 中国
  • 抗原 See all MED1 抗体
    MED1 (Mediator Complex Subunit 1 (MED1))
    抗原表位
    • 15
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 63
    • 35
    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 57
    • 4
    • 2
    • 1
    克隆类型
    • 59
    • 5
    多克隆
    标记
    • 32
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MED1 antibody is un-conjugated
    应用范围
    • 28
    • 23
    • 13
    • 13
    • 12
    • 12
    • 9
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    TRAP220/MED1 Antibody detects endogenous levels of total TRAP220/MED1.
    预测反应
    Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human TRAP220/MED1, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product MED1 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    MED1 (Mediator Complex Subunit 1 (MED1))
    别名
    MED1 (MED1 产品)
    别名
    CRSP1 antibody, CRSP200 antibody, DRIP205 antibody, DRIP230 antibody, PBP antibody, PPARBP antibody, PPARGBP antibody, RB18A antibody, TRAP220 antibody, TRIP2 antibody, CRSP-1 antibody, MED1 antibody, pbp antibody, nbr1 antibody, crsp1 antibody, rb18a antibody, trip2 antibody, pparbp antibody, crsp200 antibody, drip205 antibody, drip230 antibody, ppargbp antibody, trap220 antibody, CG7162 antibody, Dmel\\CG7162 antibody, Med1 antibody, Med1/SOP3/TRAP220 antibody, Trap220 antibody, dTRAP220 antibody, AI480703 antibody, CRSP210 antibody, Pparbp antibody, l11Jus15 antibody, RGD1559552 antibody, mediator complex subunit 1 antibody, calcitonin-related polypeptide beta antibody, Mediator complex subunit 1 antibody, mediator of RNA polymerase II transcription subunit 1 antibody, MED1 antibody, CALCB antibody, med1 antibody, Med1 antibody
    背景

    Description: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (PubMed:10406464, PubMed:11867769, PubMed:12037571, PubMed:12218053, PubMed:12556447, PubMed:14636573, PubMed:15340084, PubMed:15471764, PubMed:15989967, PubMed:16574658, PubMed:9653119). Acts as a coactivator for GATA1-mediated transcriptional activation during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781).

    Gene: MED1

    分子量
    170 kDa
    基因ID
    5469
    UniProt
    Q15648
    途径
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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