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HOPX 抗体 (C-Term)

HOPX 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257752
发货至: 中国
  • 抗原 See all HOPX 抗体
    HOPX (HOP Homeobox (HOPX))
    抗原表位
    • 15
    • 12
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 46
    • 23
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 44
    • 4
    克隆类型
    • 44
    • 4
    多克隆
    标记
    • 22
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HOPX antibody is un-conjugated
    应用范围
    • 43
    • 21
    • 14
    • 13
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    HOP Antibody detects endogenous levels of total HOP.
    预测反应
    Pig,Bovine,Horse,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human HOP, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product HOPX Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    HOPX (HOP Homeobox (HOPX))
    别名
    HOPX (HOPX 产品)
    背景

    Description: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding (PubMed:27708256).

    Gene: HOPX

    分子量
    8 kDa
    基因ID
    84525
    UniProt
    Q9BPY8
    途径
    Regulation of Muscle Cell Differentiation
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