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GNA13 抗体 (N-Term)

GNA13 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257750
发货至: 中国
  • 抗原 See all GNA13 抗体
    GNA13 (Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13))
    抗原表位
    • 15
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    N-Term
    适用
    • 45
    • 12
    • 12
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 42
    • 3
    克隆类型
    • 42
    • 3
    多克隆
    标记
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GNA13 antibody is un-conjugated
    应用范围
    • 37
    • 19
    • 14
    • 13
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    GNA13 Antibody detects endogenous levels of total GNA13.
    预测反应
    Pig,Rabbit,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human GNA13, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product GNA13 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    GNA13 (Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13))
    别名
    GNA13 (GNA13 产品)
    别名
    Galpha13 antibody, gna13 antibody, wu:fe25e05 antibody, zgc:112436 antibody, Gna13 antibody, fj64c01 antibody, wu:fj64c01 antibody, GNA13 antibody, G13 antibody, AU024132 antibody, AU043124 antibody, G protein subunit alpha 13 antibody, guanine nucleotide binding protein (G protein), alpha 13a antibody, guanine nucleotide binding protein (G protein), alpha 13b antibody, guanine nucleotide binding protein, alpha 13 antibody, Gna13 antibody, gna13a antibody, gna13b antibody, GNA13 antibody
    背景

    Description: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:15240885, PubMed:16787920, PubMed:16705036, PubMed:27084452). Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (PubMed:15240885, PubMed:12515866). GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1) (By similarity). Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway (PubMed:16787920, PubMed:16705036, PubMed:27084452). Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (PubMed:11976333).

    Gene: GNA13

    分子量
    44 kDa
    基因ID
    10672
    UniProt
    Q14344
    途径
    CXCR4-mediated Signaling Events
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