CCRL1 抗体 (C-Term)
-
- 抗原 See all CCRL1 抗体
- CCRL1 (Chemokine (C-C Motif) Receptor-Like 1 (CCRL1))
-
抗原表位
- C-Term
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CCRL1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- CCRL1 Antibody detects endogenous levels of total CCRL1.
- 预测反应
- Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CCRL1, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
-
anti-Chemokine (C-C Motif) Receptor-Like 1 (CCRL1) (Cytoplasmic Domain) antibody
CCRL1 适用: 人, 小鼠, 大鼠, 兔, 犬, 马, Pig, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 1 (CCRL1) (N-Term) antibodyCCRL1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 1 (CCRL1) (C-Term) antibodyCCRL1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 1 (CCRL1) (N-Term) antibodyCCRL1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 1 (CCRL1) (C-Term) antibodyCCRL1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 1 (CCRL1) (C-Term) antibodyCCRL1 适用: 人, 兔, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 1 (CCRL1) (C-Term) antibodyCCRL1 适用: 人, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 1 (CCRL1) (C-Term) antibodyCCRL1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 1 (CCRL1) (AA 291-340) antibodyCCRL1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 1 (CCRL1) (AA 5-54) antibodyCCRL1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- CCRL1 (Chemokine (C-C Motif) Receptor-Like 1 (CCRL1))
- 别名
- ACKR4 (CCRL1 产品)
- 别名
- CC-CKR-11 antibody, CCBP2 antibody, CCR-11 antibody, CCR10 antibody, CCR11 antibody, CCRL1 antibody, CCX CKR antibody, CCX-CKR antibody, CKR-11 antibody, PPR1 antibody, VSHK1 antibody, A630091E18Rik antibody, CCX-CKR1 antibody, Ccrl1 antibody, Cmkbrl1 antibody, atypical chemokine receptor 4 antibody, chemokine (C-C motif) receptor-like 1 antibody, Chemokine receptor-like 1 antibody, chemerin chemokine-like receptor 1 antibody, ACKR4 antibody, Ackr4 antibody, CCRL1 antibody, cml1 antibody, CMKLR1 antibody
- 背景
-
Description: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25. Chemokine-binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization. Plays an important role in controlling the migration of immune and cancer cells that express chemokine receptors CCR7 and CCR9, by reducing the availability of CCL19, CCL21, and CCL25 through internalization. Negatively regulates CXCR3-induced chemotaxis. Regulates T-cell development in the thymus.
Gene: ACKR4
- 分子量
- 40 kDa
- 基因ID
- 51554
- UniProt
- Q9NPB9
-
