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ARHGEF5 抗体 (Internal Region)

ARHGEF5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257676
发货至: 中国
  • 抗原 See all ARHGEF5 抗体
    ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))
    抗原表位
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 49
    • 16
    • 7
    • 1
    人, 小鼠, 大鼠
    宿主
    • 45
    • 3
    • 2
    • 1
    克隆类型
    • 47
    • 4
    多克隆
    标记
    • 29
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARHGEF5 antibody is un-conjugated
    应用范围
    • 35
    • 25
    • 11
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    ARHGEF5 Antibody detects endogenous levels of total ARHGEF5.
    预测反应
    Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human ARHGEF5, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ARHGEF5 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))
    别名
    ARHGEF5 (ARHGEF5 产品)
    别名
    ARHGEF5 antibody, GEF5 antibody, P60 antibody, TIM antibody, TIM1 antibody, 2210412D05Rik antibody, AA717842 antibody, AW495314 antibody, Tim1 antibody, Rho guanine nucleotide exchange factor 5 antibody, rho guanine nucleotide exchange factor 5 antibody, Rho guanine nucleotide exchange factor (GEF) 5 antibody, ARHGEF5 antibody, LOC100414419 antibody, Arhgef5 antibody
    背景

    Description: Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:15601624). Strongly activates RHOA (PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (By similarity). Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed:14662653). Required for SRC-induced podosome formation (By similarity). Involved in positive regulation of immature dendritic cell migration (By similarity).

    Gene: ARHGEF5

    分子量
    60 kDa
    基因ID
    7984
    UniProt
    Q12774
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