AKAP10 抗体 (N-Term)
-
- 抗原 See all AKAP10 抗体
- AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))
-
抗原表位
- N-Term
-
适用
- 人, 大鼠, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This AKAP10 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 特异性
- AKAP10 Antibody detects endogenous levels of total AKAP10.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human AKAP10, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product AKAP10 Primary Antibody
-
-
- 应用备注
- WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))
- 别名
- AKAP10 (AKAP10 产品)
- 别名
- MGC84612 antibody, AKAP10 antibody, fc10g11 antibody, wu:fc10g11 antibody, si:dkey-197m14.4 antibody, AKAP-10 antibody, D-AKAP-2 antibody, D-AKAP2 antibody, PRKA10 antibody, 1500031L16Rik antibody, B130049N18Rik antibody, D-akap2 antibody, Akap10 antibody, A-kinase anchoring protein 10 antibody, A-kinase anchoring protein 10 L homeolog antibody, A kinase (PRKA) anchor protein 10 antibody, AKAP10 antibody, akap10.L antibody, akap10 antibody, Akap10 antibody
- 背景
-
Description: Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity).
Gene: AKAP10
- 分子量
- 73 kDa
- 基因ID
- 11216
- UniProt
- O43572
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
-