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USP37 抗体 (Internal Region)

USP37 适用: 人, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257545
发货至: 中国
  • 抗原 See all USP37 抗体
    USP37 (Ubiquitin Specific Peptidase 37 (USP37))
    抗原表位
    • 8
    • 8
    • 8
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 36
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 36
    克隆类型
    • 36
    多克隆
    标记
    • 20
    • 4
    • 4
    • 4
    • 2
    • 2
    This USP37 antibody is un-conjugated
    应用范围
    • 24
    • 22
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    USP37 Antibody detects endogenous levels of total USP37.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human USP37, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product USP37 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    USP37 (Ubiquitin Specific Peptidase 37 (USP37))
    别名
    USP37 (USP37 产品)
    别名
    4932415L06Rik antibody, C330008N13Rik antibody, wu:fi15b04 antibody, wu:fi38d03 antibody, zgc:152882 antibody, zgc:153999 antibody, ubiquitin specific peptidase 37 antibody, USP37 antibody, usp37 antibody, Usp37 antibody
    背景

    Description: Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2) (PubMed:21596315). Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1 (PubMed:27296872).

    Gene: USP37

    分子量
    ?120 kDa
    基因ID
    57695
    UniProt
    Q86T82
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