RNF125 抗体 (Internal Region)
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- 抗原 See all RNF125 抗体
- RNF125 (Ring Finger Protein 125 (RNF125))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNF125 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- RNF125 Antibody detects endogenous levels of total RNF125.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human RNF125, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product RNF125 Primary Antibody
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anti-Ring Finger Protein 125 (RNF125) (AA 143-231) antibody
RNF125 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D3 unconjugated
anti-Ring Finger Protein 125 (RNF125) (AA 1-232) antibodyRNF125 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) (C-Term) antibodyVerified RNF125 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) (AA 143-231) antibodyRNF125 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) (AA 143-231) antibodyRNF125 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) antibodyRNF125 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) (C-Term) antibodyRNF125 适用: 人, 小鼠, 大鼠, 猴, Cow, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) (AA 1-105) antibodyRNF125 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- RNF125 (Ring Finger Protein 125 (RNF125))
- 别名
- RNF125 (RNF125 产品)
- 别名
- 4930553F04Rik antibody, TRAC-1 antibody, TRAC1 antibody, ring finger protein 125 antibody, RNF125 antibody, Rnf125 antibody
- 背景
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Description: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins, such as DDX58/RIG-I, MAVS/IPS1, IFIH1/MDA5, JAK1 and p53/TP53 (PubMed:15843525, PubMed:17460044, PubMed:17643463, PubMed:26027934, PubMed:26471729, PubMed:25591766, PubMed:27411375). Acts as a negative regulator of type I interferon production by mediating ubiquitination of DDX58/RIG-I at 'Lys-181', leading to DDX58/RIG-I degradation (PubMed:17460044, PubMed:26471729). Mediates ubiquitination and subsequent degradation of p53/TP53 (PubMed:25591766). Mediates ubiquitination and subsequent degradation of JAK1 (PubMed:26027934). Acts as a positive regulator of T-cell activation (PubMed:15843525).
Gene: RNF125
- 分子量
- 26 kDa
- 基因ID
- 54941
- UniProt
- Q96EQ8
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