NDFIP2 抗体 (Internal Region)
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- 抗原 See all NDFIP2 抗体
- NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NDFIP2 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- NDFIP2 Antibody detects endogenous levels of total NDFIP2.
- 预测反应
- Pig,Bovine,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human NDFIP2, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NDFIP2 Primary Antibody
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anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (AA 1-242) antibody
NDFIP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (AA 152-201) antibodyNDFIP2 适用: 人, 小鼠, Cow, 犬, 马, 大鼠, 斑马鱼, 豚鼠, Pig, Bat, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (AA 1-242) antibodyNDFIP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (AA 251-300) antibodyNDFIP2 适用: 人, 小鼠, Cow, 犬, 马, 大鼠, 斑马鱼, Pig, 兔, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (Middle Region) antibodyNDFIP2 适用: 人, 小鼠, Cow, 犬, 马, 大鼠, 斑马鱼, 豚鼠, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (N-Term) antibodyNDFIP2 适用: 人, 小鼠, Cow, 犬, 马, 大鼠, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))
- 别名
- NDFIP2 (NDFIP2 产品)
- 别名
- MGC68708 antibody, DKFZp459H0627 antibody, N4WBP5A antibody, 0710001O20Rik antibody, 2810436B12Rik antibody, 9130207N19Rik antibody, N4wbp5a antibody, mKIAA1165 antibody, Nedd4 family interacting protein 2 S homeolog antibody, Nedd4 family interacting protein 2 antibody, ndfip2.S antibody, NDFIP2 antibody, ndfip2 antibody, Ndfip2 antibody
- 背景
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Description: Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes. Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. Negatively regulates KCNH2 potassium channel activity by decreasing its cell-surface expression and interfering with channel maturation through recruitment of NEDD4L to the Golgi apparatus and multivesicular body where it mediates KCNH2 degradation (PubMed:26363003). May modulate EGFR signaling. Together with NDFIP1, limits the cytokine signaling and expansion of effector Th2 T-cells by promoting degradation of JAK1, probably by ITCH- and NEDD4L-mediated ubiquitination (By similarity).
Gene: NDFIP2
- 分子量
- 36 kDa
- 基因ID
- 54602
- UniProt
- Q9NV92
- 途径
- Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome
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