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- 抗原 See all NCOA1 抗体
- NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NCOA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- NCOA1 antibody detects endogenous levels of total NCOA1
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide
- 亚型
- IgG
- Top Product
- Discover our top product NCOA1 Primary Antibody
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anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 1222-1441) antibody
NCOA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) antibodyNCOA1 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 1338-1367) antibodyNCOA1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (pTyr529) antibodyNCOA1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 201-300) antibodyNCOA1 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 284-393) antibodyNCOA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) antibodyNCOA1 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (N-Term) antibodyNCOA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 611-660) antibodyNCOA1 适用: 人, 大鼠, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) antibodyNCOA1 适用: 人 DB 宿主: 小鼠 Monoclonal 3532C6a unconjugated
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- 应用备注
- WB 1:500-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- 抗原
- NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
- 别名
- NCOA1 (NCOA1 产品)
- 别名
- F-SRC-1 antibody, KAT13A antibody, RIP160 antibody, SRC1 antibody, bHLHe42 antibody, bHLHe74 antibody, si:dkey-5g7.6 antibody, si:dkey-34f16.6 antibody, NCOA1 antibody, SRC-1 antibody, nuclear receptor coactivator 1 antibody, NCOA1 antibody, ncoa1 antibody, Ncoa1 antibody
- 背景
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Description: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4, the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues. Required for mediating steroid hormone response. Isoform 2 has a higher thyroid hormone-dependent transactivation activity than isoform 1 and isoform 3.
Gene: NCOA1
- 分子量
- 200 kDa
- 基因ID
- 8648
- UniProt
- Q15788
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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