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MYO9B 抗体 (N-Term)

MYO9B 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257337
发货至: 中国
  • 抗原 See all MYO9B 抗体
    MYO9B (Myosin IXB (MYO9B))
    抗原表位
    • 2
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 11
    • 1
    克隆类型
    • 12
    多克隆
    标记
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYO9B antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    MYO9B Antibody detects endogenous levels of total MYO9B.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human MYO9B, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    MYO9B (Myosin IXB (MYO9B))
    别名
    MYO9B (MYO9B 产品)
    别名
    CELIAC4 antibody, MYR5 antibody, MYO9B antibody, fb53f01 antibody, wu:fb53f01 antibody, wu:fc47c07 antibody, si:dkeyp-66d1.8 antibody, myosin IXB antibody, myosin IXb antibody, unconventional myosin-IXb antibody, MYO9B antibody, Myo9b antibody, myo9b antibody, LOC100450445 antibody
    背景

    Description: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions (PubMed:9490638). Also acts as a GTPase activator for RHOA (PubMed:9490638, PubMed:26529257). Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. This is regulated by its interaction with the SLIT2 receptor ROBO1, interaction with ROBO1 impairs interaction with RHOA and subsequent activation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA (PubMed:26529257).

    Gene: MYO9B

    分子量
    250 kDa
    基因ID
    4650
    UniProt
    Q13459
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