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Kallikrein 6 抗体 (C-Term)

KLK6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257305
发货至: 中国
  • 抗原 See all Kallikrein 6 (KLK6) 抗体
    Kallikrein 6 (KLK6)
    抗原表位
    • 15
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    C-Term
    适用
    • 39
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    宿主
    • 57
    • 5
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    克隆类型
    • 59
    • 5
    多克隆
    标记
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    This Kallikrein 6 antibody is un-conjugated
    应用范围
    • 49
    • 21
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    • 10
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    • 5
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    KLK6 Antibody detects endogenous levels of total KLK6.
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human KLK6, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product KLK6 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    Kallikrein 6 (KLK6)
    别名
    KLK6 (KLK6 产品)
    别名
    Bssp antibody, Klk7 antibody, PRSS18 antibody, PRSS9 antibody, SP59 antibody, hK6 antibody, Prss9 antibody, AI849898 antibody, BSP antibody, Klk29 antibody, MSP antibody, Prss18 antibody, neurosin antibody, kallikrein related peptidase 6 antibody, kallikrein related-peptidase 6 antibody, kallikrein-6 antibody, KLK6 antibody, Klk6 antibody, LOC100716801 antibody
    背景

    Description: Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis.

    Gene: KLK6

    分子量
    30 kDa
    基因ID
    5653
    UniProt
    Q92876
    途径
    Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
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