IL-11 抗体 (N-Term)
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- 抗原 See all IL-11 (IL11) 抗体
- IL-11 (IL11) (Interleukin 11 (IL11))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL-11 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- IL11 Antibody detects endogenous levels of total IL11.
- 预测反应
- Pig,Bovine,Horse,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human IL11, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product IL11 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- IL-11 (IL11) (Interleukin 11 (IL11))
- 别名
- IL11 (IL11 产品)
- 别名
- IL11 antibody, AGIF antibody, IL-11 antibody, Il-11 antibody, interleukin 11 antibody, IL11 antibody, Il11 antibody
- 背景
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Description: Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.
Gene: IL11
- 分子量
- 27 kDa
- 基因ID
- 3589
- UniProt
- P20809
- 途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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