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ING4 抗体 (Internal Region)

ING4 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257280
发货至: 中国
  • 抗原 See all ING4 抗体
    ING4 (Inhibitor of Growth Family, Member 4 (ING4))
    抗原表位
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 29
    • 16
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 25
    • 3
    • 1
    克隆类型
    • 28
    • 1
    多克隆
    标记
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ING4 antibody is un-conjugated
    应用范围
    • 17
    • 11
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    ING4 Antibody detects endogenous levels of total ING4.
    预测反应
    Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human ING4, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ING4 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    ING4 (Inhibitor of Growth Family, Member 4 (ING4))
    别名
    ING4 (ING4 产品)
    别名
    wu:fb11d09 antibody, wu:fb50e02 antibody, zgc:110619 antibody, ING4 antibody, my036 antibody, p29ING4 antibody, D6Wsu147e antibody, D6Xrf92 antibody, inhibitor of growth family, member 4 antibody, inhibitor of growth family member 4 antibody, ing4 antibody, ING4 antibody, Ing4 antibody
    背景

    Description: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). Can enhance apoptosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity).

    Gene: ING4

    分子量
    29 kDa
    基因ID
    51147
    UniProt
    Q9UNL4
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