XRN1 抗体 (N-Term)
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- 抗原 See all XRN1 抗体
- XRN1 (5'-3' Exoribonuclease 1 (XRN1))
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This XRN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), ELISA, Immunofluorescence (IF)
- 特异性
- XRN1 Antibody detects endogenous levels of total XRN1.
- 预测反应
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human XRN1, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product XRN1 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- XRN1 (5'-3' Exoribonuclease 1 (XRN1))
- 别名
- XRN1 (XRN1 产品)
- 别名
- wu:fk92c07 antibody, zgc:63635 antibody, SEP1 antibody, Dhm2 antibody, exo antibody, mXrn1 antibody, RGD1309713 antibody, 5'-3' exoribonuclease 1 antibody, xrn1 antibody, XRN1 antibody, Tsp_05930 antibody, Xrn1 antibody
- 背景
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Description: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
Gene: XRN1
- 分子量
- 194 kDa
- 基因ID
- 54464
- UniProt
- Q8IZH2
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