Foxk1 抗体 (Internal Region)
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- 抗原 See all Foxk1 抗体
- Foxk1 (Forkhead Box K1 (Foxk1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Foxk1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- FOXK1 Antibody detects endogenous levels of total FOXK1.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human FOXK1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product Foxk1 Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- Foxk1 (Forkhead Box K1 (Foxk1))
- 别名
- FOXK1 (Foxk1 产品)
- 别名
- FOXK1L antibody, A630048H08Rik antibody, AI463295 antibody, ENSMUSG00000075577 antibody, Gm10868 antibody, Mnf antibody, RGD1309643 antibody, wu:fi75f05 antibody, zgc:66237 antibody, FOXK1 antibody, forkhead box K1 antibody, FOXK1 antibody, Foxk1 antibody, foxk1 antibody
- 背景
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Description: Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene (By similarity). Important regulatory factor of the myogenic progenitor cell population (By similarity). Involved in the cell cycle process, promotes proliferation by repressing Foxo4 transcriptional activity and the cyclin-dependent kinase inhibitor, p21CIP, in the myogenic progenitor cells (By similarity). Represses myogenic differentiation by inhibiting MEFC acitivity (By similarity). Has a role in remodeling processes of adult muscles that occur in response to physiological stimuli (By similarity). Required to correct temporal orchestration of molecular and cellular events necessary for muscle repair (By similarity). Positively regulates Wnt/beta-catenin signaling by translocating DVL into the nucleus (PubMed:25805136). Reduces virus replication, probably by binding the interferon stimulated response element (ISRE) to promote antiviral gene expression (PubMed:25852164).
Gene: FOXK1
- 分子量
- 78 kDa
- 基因ID
- 221937
- UniProt
- P85037
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