EIF3K 抗体 (N-Term)
-
- 抗原 See all EIF3K 抗体
- EIF3K (Eukaryotic Translation Initiation Factor 3 Subunit K (EIF3K))
-
抗原表位
- N-Term
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This EIF3K antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- EIF3K Antibody detects endogenous levels of total EIF3K.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human EIF3K, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product EIF3K Primary Antibody
-
-
- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- EIF3K (Eukaryotic Translation Initiation Factor 3 Subunit K (EIF3K))
- 别名
- EIF3K (EIF3K 产品)
- 别名
- eif3s12 antibody, EIF3S12 antibody, ACYPI000023 antibody, eIF3k antibody, EIF3-p28 antibody, HSPC029 antibody, M9 antibody, MSTP001 antibody, PLAC-24 antibody, PLAC24 antibody, PRO1474 antibody, PTD001 antibody, 1200009C21Rik antibody, Eif3s12 antibody, zgc:110726 antibody, eukaryotic translation initiation factor 3 subunit K L homeolog antibody, eukaryotic translation initiation factor 3 subunit K antibody, eukaryotic translation initiation factor 3, subunit K antibody, eukaryotic translation initiation factor 3 subunit k antibody, Eukaryotic translation initiation factor 3 subunit K antibody, eif3k.L antibody, EIF3K antibody, eif3k antibody, ANI_1_1610144 antibody, AOR_1_2266174 antibody, Tsp_00068 antibody, Tsp_13184 antibody, Eif3k antibody, LOC733122 antibody, eif-3.K antibody
- 背景
-
Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
Gene: EIF3K
- 分子量
- 30 kDa
- 基因ID
- 27335
- UniProt
- Q9UBQ5
- 途径
- Ribonucleoprotein Complex Subunit Organization
-