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EIF3K 抗体 (N-Term)

EIF3K 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257176
发货至: 中国
  • 抗原 See all EIF3K 抗体
    EIF3K (Eukaryotic Translation Initiation Factor 3 Subunit K (EIF3K))
    抗原表位
    • 15
    • 10
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 57
    • 13
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 55
    • 2
    克隆类型
    • 55
    • 2
    多克隆
    标记
    • 27
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EIF3K antibody is un-conjugated
    应用范围
    • 47
    • 20
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    EIF3K Antibody detects endogenous levels of total EIF3K.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human EIF3K, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product EIF3K Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    EIF3K (Eukaryotic Translation Initiation Factor 3 Subunit K (EIF3K))
    别名
    EIF3K (EIF3K 产品)
    别名
    eif3s12 antibody, EIF3S12 antibody, ACYPI000023 antibody, eIF3k antibody, EIF3-p28 antibody, HSPC029 antibody, M9 antibody, MSTP001 antibody, PLAC-24 antibody, PLAC24 antibody, PRO1474 antibody, PTD001 antibody, 1200009C21Rik antibody, Eif3s12 antibody, zgc:110726 antibody, eukaryotic translation initiation factor 3 subunit K L homeolog antibody, eukaryotic translation initiation factor 3 subunit K antibody, eukaryotic translation initiation factor 3, subunit K antibody, eukaryotic translation initiation factor 3 subunit k antibody, Eukaryotic translation initiation factor 3 subunit K antibody, eif3k.L antibody, EIF3K antibody, eif3k antibody, ANI_1_1610144 antibody, AOR_1_2266174 antibody, Tsp_00068 antibody, Tsp_13184 antibody, Eif3k antibody, LOC733122 antibody, eif-3.K antibody
    背景

    Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).

    Gene: EIF3K

    分子量
    30 kDa
    基因ID
    27335
    UniProt
    Q9UBQ5
    途径
    Ribonucleoprotein Complex Subunit Organization
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