DRD4 抗体 (C-Term)
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- 抗原 See all DRD4 抗体
- DRD4 (Dopamine Receptor D4 (DRD4))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DRD4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- DRD4 Antibody detects endogenous levels of total DRD4.
- 预测反应
- Pig,Bovine,Horse,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human DRD4, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- DRD4 (Dopamine Receptor D4 (DRD4))
- 别名
- DRD4 (DRD4 产品)
- 别名
- Drd4b antibody, si:ch211-69h5.1 antibody, zgc:123021 antibody, D4DR antibody, AW125663 antibody, D4R antibody, Drd-4 antibody, D4RA antibody, DRD4 antibody, Drd4c antibody, dopamine receptor D4 related sequence antibody, dopamine receptor D4 antibody, dopamine receptor D4b antibody, drd4-rs antibody, DRD4 antibody, Drd4 antibody, SRU_2808 antibody, MSMEG_3522 antibody, drd4b antibody
- 背景
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Description: Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Activated by dopamine, but also by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs (PubMed:9003072, PubMed:16423344, PubMed:27659709, PubMed:29051383). Agonist binding triggers signaling via G proteins that inhibit adenylyl cyclase (PubMed:7512953, PubMed:7643093, PubMed:16423344, PubMed:27659709, PubMed:29051383). Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells (By similarity).
Gene: DRD4
- 分子量
- 48 kDa
- 基因ID
- 1815
- UniProt
- P21917
- 途径
- cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity
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