DKC1 抗体 (Internal Region)
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- 抗原 See all DKC1 抗体
- DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DKC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- DKC1 Antibody detects endogenous levels of total DKC1.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human DKC1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product DKC1 Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
- 别名
- DKC1 (DKC1 产品)
- 别名
- CBF5 antibody, DKC antibody, DKCX antibody, NAP57 antibody, NOLA4 antibody, XAP101 antibody, dyskerin antibody, fv62a07 antibody, wu:fa28f10 antibody, wu:fc87a02 antibody, wu:fi24a05 antibody, wu:fv62a07 antibody, zgc:110395 antibody, DKC1 antibody, cbf5 antibody, dkc antibody, nap57 antibody, nola4 antibody, xap101 antibody, BC068171 antibody, Nap57 antibody, AtCBF5 antibody, AtNAP57 antibody, homologue of NAP57 antibody, dyskerin pseudouridine synthase 1 antibody, microRNA 664b antibody, dyskeratosis congenita 1, dyskerin antibody, dyskeratosis congenita 1, dyskerin L homeolog antibody, homologue of NAP57 antibody, DKC1 antibody, MIR664B antibody, dkc1 antibody, dkc1.L antibody, Dkc1 antibody, NAP57 antibody
- 背景
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Description: Isoform 1: Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
Gene: DKC1
- 分子量
- 57 kDa
- 基因ID
- 1736
- UniProt
- O60832
- 途径
- Telomere Maintenance
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