Cyclin T2 抗体 (Internal Region)
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- 抗原 See all Cyclin T2 (CCNT2) 抗体
- Cyclin T2 (CCNT2)
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抗原表位
- Internal Region
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cyclin T2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- CCNT2 Antibody detects endogenous levels of total CCNT2.
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CCNT2, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CCNT2 Primary Antibody
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anti-Cyclin T2 (CCNT2) (C-Term) antibody
CCNT2 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin T2 (CCNT2) (AA 264-370) antibodyCCNT2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H3 unconjugated
anti-Cyclin T2 (CCNT2) antibodyCCNT2 适用: 人 WB, DB 宿主: 小鼠 Monoclonal 2128C1a unconjugated
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- 应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- Cyclin T2 (CCNT2)
- 别名
- CCNT2 (CCNT2 产品)
- 别名
- fb16c03 antibody, wu:fb16c03 antibody, wu:fj68b10 antibody, zgc:55690 antibody, ccnt2 antibody, cycT antibody, wu:fi17h07 antibody, zgc:55357 antibody, MGC81210 antibody, CCNT2 antibody, CYCT2 antibody, 2900041I18Rik antibody, C81304 antibody, CycT2 antibody, CycT2b antibody, cyclin T2 antibody, cyclin T2b antibody, cyclin T2a antibody, cyclin T2 S homeolog antibody, CCNT2 antibody, ccnt2b antibody, ccnt2a antibody, ccnt2.S antibody, ccnt2 antibody, Ccnt2 antibody
- 背景
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Description: Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II) (PubMed:9499409, PubMed:15563843). The activity of this complex is regulated by binding with 7SK snRNA (PubMed:11713533). Plays a role during muscle differentiation, P-TEFB complex interacts with MYOD1, this tripartite complex promotes the transcriptional activity of MYOD1 through its CDK9-mediated phosphorylation and binds the chromatin of promoters and enhancers of muscle-specific genes, this event correlates with hyperphosphorylation of the CTD domain of RNA pol II (By similarity). In addition, enhances MYOD1-dependent transcription through interaction with PKN1 (PubMed:16331689). Involved in early embryo development (By similarity).
Gene: CCNT2
- 分子量
- 81kDa
- 基因ID
- 905
- UniProt
- O60583
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