CLASP1 抗体 (Internal Region)
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- 抗原 See all CLASP1 抗体
- CLASP1 (Cytoplasmic Linker Associated Protein 1 (CLASP1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CLASP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- CLASP1 Antibody detects endogenous levels of total CLASP1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CLASP1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CLASP1 (Cytoplasmic Linker Associated Protein 1 (CLASP1))
- 别名
- CLASP1 (CLASP1 产品)
- 别名
- Xorbit antibody, clasp1 antibody, clasp1b antibody, mast1 antibody, CLASP1 antibody, 1700030C23Rik antibody, 5730583A19Rik antibody, B130045P17Rik antibody, mKIAA0622 antibody, MAST1 antibody, cytoplasmic linker associated protein 1 S homeolog antibody, cytoplasmic linker associated protein 1b antibody, cytoplasmic linker associated protein 1 antibody, CLIP-associating protein 1 antibody, CLIP associating protein 1 antibody, clasp1.S antibody, clasp1b antibody, CLASP1 antibody, clasp1 antibody, LOC100078792 antibody, Clasp1 antibody
- 背景
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Description: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
Gene: CLASP1
- 分子量
- 169 kDa
- 基因ID
- 23332
- UniProt
- Q7Z460
- 途径
- Microtubule Dynamics, M Phase, Maintenance of Protein Location
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