CDK5RAP3 抗体
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- 抗原 See all CDK5RAP3 抗体
- CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDK5RAP3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- CDK5RAP3 Antibody detects endogenous levels of total CDK5RAP3
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide
- 亚型
- IgG
- Top Product
- Discover our top product CDK5RAP3 Primary Antibody
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anti-CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3) (AA 1-506) antibody
CDK5RAP3 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G4 unconjugated
anti-CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3) antibodyCDK5RAP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3) (AA 42-292), (Regulatory Subunit) antibodyCDK5RAP3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3) (AA 341-390) antibodyCDK5RAP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3) (AA 1-300) antibodyCDK5RAP3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3) (AA 1-300) antibodyCDK5RAP3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500~1:1000, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))
- 别名
- CDK5RAP3 (CDK5RAP3 产品)
- 别名
- cdkrap3 antibody, fb33h04 antibody, fc09c05 antibody, id:ibd2920 antibody, wu:fb33h04 antibody, wu:fc09c05 antibody, zgc:86863 antibody, CDK5RAP3 antibody, cdk5rap3 antibody, MGC82350 antibody, C53 antibody, HSF-27 antibody, IC53 antibody, LZAP antibody, MST016 antibody, OK/SW-cl.114 antibody, PP1553 antibody, 1810007E24Rik antibody, BC002318 antibody, C81486 antibody, CDK5 regulatory subunit associated protein 3 antibody, CDK5 regulatory subunit associated protein 3 L homeolog antibody, cdk5rap3 antibody, CDK5RAP3 antibody, cdk5rap3.L antibody, Cdk5rap3 antibody
- 背景
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Description: Probable tumor suppressor initially identified as a CDK5R1 interactor controlling cell proliferation (PubMed:12054757, PubMed:12737517). Negatively regulates NF-kappa-B-mediated gene transcription through the control of RELA phosphorylation (PubMed:17785205, PubMed:20228063). Also regulates mitotic G2/M transition checkpoint and mitotic G2 DNA damage checkpoint (PubMed:15790566, PubMed:19223857). Through its interaction with CDKN2A/ARF and MDM2 may induce MDM2-dependent p53/TP53 ubiquitination, stabilization and activation in the nucleus, thereby promoting G1 cell cycle arrest and inhibition of cell proliferation (PubMed:16173922). May play a role in the unfolded protein response, mediating the ufmylation of multiple proteins in response to endoplasmic reticulum stress (PubMed:23152784). May also play a role in the rupture of the nuclear envelope during apoptosis (PubMed:23478299). May regulate MAPK14 activity by regulating its dephosphorylation by PPM1D/WIP1 (PubMed:21283629).
Gene: CDK5RAP3
- 分子量
- 60 kDa
- 基因ID
- 80279
- UniProt
- Q96JB5
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