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ARHGAP17 抗体 (Internal Region)

ARHGAP17 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257043
发货至: 中国
  • 抗原 See all ARHGAP17 抗体
    ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))
    抗原表位
    • 10
    • 9
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 34
    • 12
    • 11
    • 2
    人, 大鼠, 小鼠
    宿主
    • 36
    克隆类型
    • 35
    多克隆
    标记
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARHGAP17 antibody is un-conjugated
    应用范围
    • 28
    • 19
    • 14
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    RHG17 Antibody detects endogenous levels of total RHG17.
    预测反应
    Bovine,Horse,Rabbit,Dog,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human RHG17, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ARHGAP17 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))
    别名
    ARHGAP17 (ARHGAP17 产品)
    别名
    MST066 antibody, MST110 antibody, MSTP038 antibody, MSTP066 antibody, MSTP110 antibody, NADRIN antibody, PP367 antibody, PP4534 antibody, RICH1 antibody, RICH1B antibody, WBP15 antibody, 5730403H17Rik antibody, Nadrin antibody, Nadrin2 antibody, Rich1 antibody, Wbp15 antibody, Rho GTPase activating protein 17 antibody, ARHGAP17 antibody, arhgap17 antibody, Arhgap17 antibody
    背景

    Description: Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca2+-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.

    Gene: ARHGAP17

    分子量
    100 kDa
    基因ID
    55114
    UniProt
    Q68EM7
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