BRMS1 抗体 (N-Term)
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- 抗原 See all BRMS1 抗体
- BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BRMS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- BRMS1 Antibody detects endogenous levels of total BRMS1.
- 预测反应
- Pig,Horse,Sheep,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human BRMS1, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product BRMS1 Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
- 别名
- BRMS1 (BRMS1 产品)
- 别名
- MGC98869 antibody, BRMS1 antibody, BRMS1L antibody, AV003220 antibody, AW554636 antibody, si:zc188c22.3 antibody, si:zc194c5.2 antibody, wu:fb57b08 antibody, zgc:56414 antibody, breast cancer metastasis suppressor 1 antibody, breast cancer metastasis-suppressor 1 antibody, breast cancer metastasis suppressor 1 L homeolog antibody, BRMS1 antibody, Brms1 antibody, brms1.L antibody, brms1 antibody
- 背景
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Description: Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
Gene: BRMS1
- 分子量
- 28 kDa
- 基因ID
- 25855
- UniProt
- Q9HCU9
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