我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

Serotonin Receptor 2B 抗体 (Internal Region)

Name: Serotonin Receptor 2B 抗体 (Internal Region)
SKU: ABIN6256878
Availability: OutOfStock

HTR2B 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts from HepG2, using 5-HT-2B Antibody. (Serotonin Receptor 2B 抗体 (Internal Region))

ABIN6274572 at 1/100 staining Human liver cancer tissue by IHC-P. (Serotonin Receptor 2B 抗体 (Internal Region))

IHC

IF/ICC

Western blot analysis of extracts from HeLa cells, using 5-HT-2B antibody. (Serotonin Receptor 2B 抗体 (Internal Region))

4 images

产品编号 ABIN6256878

发货至: 中国

Datasheet as PDF

抗原 See all Serotonin Receptor 2B (HTR2B) 抗体

Serotonin Receptor 2B (HTR2B)
抗原表位
15

7

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Internal Region
适用
52

13

12

2

2

2

2

1
人, 小鼠
宿主
49

3
兔
Compatible Secondaries
克隆类型
50

2
多克隆
标记
26

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Serotonin Receptor 2B antibody is un-conjugated
应用范围
37

14

13

13

10

10

7

3

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

5HT2B Receptor Antibody detects endogenous levels of total 5HT2B Receptor.

预测反应

Horse,Chicken

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human 5HT2B Receptor, corresponding to a region within the internal amino acids.

亚型

IgG
anti-Serotonin Receptor 2B (HTR2B) (N-Term) antibody
HTR2B 适用: 人, 豚鼠, Pig, Cow, 犬, 马 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Serotonin Receptor 2B (HTR2B) (AA 382-481) antibody
HTR2B 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Serotonin Receptor 2B (HTR2B) antibody
HTR2B 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Serotonin Receptor 2B (HTR2B) (AA 408-435), (C-Term) antibody
HTR2B 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB20470 unconjugated

anti-Serotonin Receptor 2B (HTR2B) (AA 1-56) antibody
HTR2B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Serotonin Receptor 2B (HTR2B) (AA 382-481) antibody
HTR2B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Serotonin Receptor 2B (HTR2B) (AA 261-310) antibody
HTR2B 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Serotonin Receptor 2B (HTR2B) (N-Term) antibody
HTR2B 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Serotonin Receptor 2B (HTR2B) (AA 1-481) antibody
HTR2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Serotonin Receptor 2B (HTR2B) (AA 1-56) antibody
HTR2B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A4 unconjugated

应用备注

WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

Serotonin Receptor 2B (HTR2B)

别名

HTR2B (HTR2B 产品)

别名

5-HT2B antibody, 5HT2B antibody, 5htr2b antibody, HTR2B antibody, 5ht2b antibody, zgc:194094 antibody, zgc:194119 antibody, AJ012488 antibody, AV377389 antibody, 5-HT(2B) antibody, 5-hydroxytryptamine receptor 2B antibody, 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled antibody, 5-hydroxytryptamine (serotonin) receptor 2B antibody, HTR2B antibody, htr2b antibody, Htr2b antibody

背景

Description: G-protein coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:8143856, PubMed:7926008, PubMed:8078486, PubMed:8882600, PubMed:18703043, PubMed:23519210). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances (PubMed:8143856, PubMed:7926008, PubMed:8078486, PubMed:12970106, PubMed:18703043, PubMed:23519210, PubMed:23519215, PubMed:24357322, PubMed:28129538). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors (PubMed:8143856, PubMed:8078486, PubMed:8882600, PubMed:23519215, PubMed:28129538). Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways (PubMed:23519215, PubMed:28129538). Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores (PubMed:8143856, PubMed:8078486, PubMed:8882600, PubMed:18703043, PubMed:23519215, PubMed:28129538). Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects neural activity. May play a role in the perception of pain (By similarity). Plays a role in the regulation of behavior, including impulsive behavior (PubMed:21179162). Required for normal proliferation of embryonic cardiac myocytes and normal heart development. Protects cardiomyocytes against apoptosis. Plays a role in the adaptation of pulmonary arteries to chronic hypoxia. Plays a role in vasoconstriction. Required for normal osteoblast function and proliferation, and for maintaining normal bone density. Required for normal proliferation of the interstitial cells of Cajal in the intestine (By similarity).
Gene: HTR2B

分子量

54 kDa

基因ID

3357

UniProt

P41595

途径

JAK/STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process