5HT1B Receptor 抗体 (Internal Region)
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- 抗原 See all 5HT1B Receptor (HTR1B) 抗体
- 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))
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抗原表位
- Internal Region
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This 5HT1B Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- 特异性
- 5HT1B Receptor Antibody detects endogenous levels of total 5HT1B Receptor.
- 预测反应
- Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human 5HT1B Receptor, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product HTR1B Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))
- 别名
- HTR1B (HTR1B 产品)
- 别名
- 5-HT1B antibody, 5-HT1DB antibody, HTR1D2 antibody, HTR1DB antibody, S12 antibody, 5-HT1Db antibody, 5-HT1-LIKE antibody, HTR1B antibody, 5-HT-dro2B antibody, 5-HT1BDro antibody, 5-HT[1B]Dro antibody, 5-HT[[1BDro]] antibody, 5-HT[[1B]] antibody, 5-HT[[1B]]DRO antibody, 5-HT[[1B]]Dro antibody, 5-HT[[dro2B]] antibody, 5HT-R2B antibody, 5HT-dro2B antibody, 5HT-dro[[2B]] antibody, 5HT1B antibody, 5htdro2b antibody, CG15113 antibody, CG30126 antibody, DRO2B antibody, Dm5HTdro2B antibody, Dmel\\CG15113 antibody, Dmel_CG30126 antibody, d5-HT1B antibody, 5-HT-1B antibody, zgc:194666 antibody, zgc:194690 antibody, 5-hydroxytryptamine receptor 1B antibody, 5-hydroxytryptamine (serotonin) receptor 1B antibody, HTR1B antibody, Htr1b antibody, 5-HT1B antibody, htr1b antibody
- 背景
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Description: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
Gene: HTR1B
- 分子量
- 44 kDa
- 基因ID
- 3351
- UniProt
- P28222
- 途径
- JAK/STAT Signaling, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, S100 Proteins
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