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TNFSF18 抗体

TNFSF18 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6256856
发货至: 中国
  • 抗原 See all TNFSF18 抗体
    TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
    适用
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    宿主
    • 51
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    克隆类型
    • 50
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    多克隆
    标记
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    This TNFSF18 antibody is un-conjugated
    应用范围
    • 53
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    TNF18 antibody detects endogenous levels of total TNF18
    交叉反应
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide
    亚型
    IgG
    Top Product
    Discover our top product TNFSF18 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
    别名
    TNF18 (TNFSF18 产品)
    别名
    Gitrl antibody, AITRL antibody, GITRL antibody, TL6 antibody, hGITRL antibody, TNLG2A antibody, tumor necrosis factor (ligand) superfamily, member 18 antibody, TNF superfamily member 18 antibody, Tnfsf18 antibody, TNFSF18 antibody
    背景

    Description: Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation (By similarity).

    Gene: TNFSF18

    分子量
    72 kDa
    基因ID
    8995
    UniProt
    Q9UNG2
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