EPS15 抗体 (pTyr849)
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- 抗原 See all EPS15 抗体
- EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
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抗原表位
- pTyr849
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EPS15 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Phospho-EPS15 (Tyr849) Antibody detects endogenous levels of EPS15 only when phosphorylated at Tyrosine 849.
- 纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- 免疫原
- A synthesized peptide derived from human EPS15 around the phosphorylation site of Tyr849.
- 亚型
- IgG
- Top Product
- Discover our top product EPS15 Primary Antibody
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anti-Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) (AA 660-840) antibody
EPS15 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) antibodyEPS15 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) (pTyr849) antibodyEPS15 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) (pTyr849) antibodyEPS15 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) (AA 794-843) antibodyEPS15 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 豚鼠, 猴, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) (C-Term) antibodyEPS15 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) (AA 2-88) antibodyEPS15 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) (C-Term) antibodyEPS15 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
- 别名
- EPS15 (EPS15 产品)
- 背景
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Description: Involved in cell growth regulation. May be involved in the regulation of mitogenic signals and control of cell proliferation. Involved in the internalization of ligand-inducible receptors of the receptor tyrosine kinase (RTK) type, in particular EGFR. Plays a role in the assembly of clathrin-coated pits (CCPs). Acts as a clathrin adapter required for post-Golgi trafficking. Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR), internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.
Gene: EPS15
- 分子量
- 98kDa
- 基因ID
- 2060
- UniProt
- P42566
- 途径
- EGFR Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, EGFR Downregulation
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