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Caspase 9 抗体 (pThr125)

CASP9 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6256471
发货至: 中国
  • 抗原 See all Caspase 9 (CASP9) 抗体
    Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
    抗原表位
    • 28
    • 16
    • 16
    • 16
    • 16
    • 8
    • 5
    • 5
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    • 1
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    • 1
    • 1
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    pThr125
    适用
    • 210
    • 128
    • 103
    • 18
    • 17
    • 16
    • 7
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 206
    • 14
    克隆类型
    • 194
    • 26
    多克隆
    标记
    • 109
    • 10
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
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    • 4
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    • 1
    This Caspase 9 antibody is un-conjugated
    应用范围
    • 189
    • 74
    • 67
    • 67
    • 63
    • 44
    • 37
    • 36
    • 18
    • 16
    • 15
    • 5
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Phospho-Caspase 9 (Thr125) Antibody detects endogenous levels of Caspase 9 only when phosphorylated at Threonine 125.
    预测反应
    Pig,Bovine,Horse,Sheep
    纯化方法
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    免疫原
    A synthesized peptide derived from human Caspase 9 around the phosphorylation site of Thr125.
    亚型
    IgG
    Top Product
    Discover our top product CASP9 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
    别名
    CASP9 (CASP9 产品)
    背景

    Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

    Gene: CASP9

    分子量
    47kDa
    基因ID
    842
    UniProt
    P55211
    途径
    MAPK Pathway, RTK signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
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