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Lamin A/C 抗体 (pSer392)

LMNA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of Lamin A/C phosphorylation expression in HeLa whole cell lysates,The lane on the left is treated with the antigen-specific peptide. (Lamin A/C 抗体 (pSer392))

ABIN6267273 staining HeLa cells by ICC/IF. (Lamin A/C 抗体 (pSer392))

ABIN6267273 at 1/100 staining human appendiceal tissue sections by IHC-P. (Lamin A/C 抗体 (pSer392))

ABIN6267273 staining HeLa by IF/ICC. (Lamin A/C 抗体 (pSer392))

ABIN6267273 at 1/100 staining mouse testis tissue sections by IHC-P. (Lamin A/C 抗体 (pSer392))

ABIN6267273 at 1/100 staining rat uterine tissue sections by IHC-P. (Lamin A/C 抗体 (pSer392))

Western blot analysis of Phospho-Lamin A/C (Ser392) expression in various lysates (Lamin A/C 抗体 (pSer392))

ABIN6267273 at 1/100 staining mouse brain tissue sections by IHC-P. (Lamin A/C 抗体 (pSer392))

ABIN6267273 at 1/100 staining human liver tissue sections by IHC-P. (Lamin A/C 抗体 (pSer392))

ABIN6267273 at 1/100 staining mouse spleen tissue sections by IHC-P. (Lamin A/C 抗体 (pSer392))

ABIN6267273 at 1/100 staining human skin tissue sections by IHC-P. (Lamin A/C 抗体 (pSer392))

ABIN6267273 at 1/100 staining rat gastric tissue sections by IHC-P. (Lamin A/C 抗体 (pSer392))

ABIN6267273 at 1/100 staining rat spleen tissue sections by IHC-P. (Lamin A/C 抗体 (pSer392))

ABIN6267273 at 1/100 staining rat liver tissue sections by IHC-P. (Lamin A/C 抗体 (pSer392))

14 images

产品编号 ABIN6256311

发货至: 中国

Datasheet as PDF

抗原 See all Lamin A/C (LMNA) 抗体

Lamin A/C (LMNA)
抗原表位
10

8

7

6

5

4

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer392
适用
131

72

70

27

15

13

8

7

6

6

6

4

4

3

3

2

2

1

1

1

1

1

1
人, 小鼠, 大鼠
宿主
96

45

2

1
兔
Compatible Secondaries
克隆类型
95

49
多克隆
标记
113

9

8

6

2

2

2

2
This Lamin A/C antibody is un-conjugated
应用范围
119

54

53

47

32

31

29

20

15

7

3

2

2

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

Phospho-Lamin A/C (Ser392) Antibody detects endogenous levels of Lamin A/C only when phosphorylated at Serine 392.

预测反应

Pig,Zebrafish,Bovine,Horse,Rabbit,Chicken,Xenopus

纯化方法

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

免疫原

A synthesized peptide derived from human Lamin A/C around the phosphorylation site of Ser392.

亚型

IgG

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anti-Lamin A/C (LMNA) (C-Term) antibody
LMNA 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 猴, 马, 兔, Hamster, 小鸡, 绵羊, 豚鼠, Avian, Cat, 驴, 山羊 WB 宿主: 山羊 Polyclonal unconjugated

anti-Lamin A/C (LMNA) (AA 1-664) antibody
LMNA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

Lamin A/C (LMNA)

别名

LMNA (LMNA 产品)

背景

Description: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation (PubMed:10080180, PubMed:22431096, PubMed:10814726, PubMed:11799477, PubMed:18551513). Required for osteoblastogenesis and bone formation (PubMed:12075506, PubMed:15317753, PubMed:18611980). Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone (PubMed:10587585). Required for cardiac homeostasis (PubMed:10580070, PubMed:12927431, PubMed:18611980, PubMed:23666920).
Gene: LMNA

分子量

74,65kDa

基因ID

4000

UniProt

P02545

途径

Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus

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