Aryl Hydrocarbon Receptor 抗体 (pSer36)
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- 抗原 See all Aryl Hydrocarbon Receptor (AHR) 抗体
- Aryl Hydrocarbon Receptor (AHR)
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抗原表位
- pSer36
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Aryl Hydrocarbon Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Phospho-AhR (Ser36) Antibody detects endogenous levels of AhR only when phosphorylated at Serine 36
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- 免疫原
- A synthesized peptide derived from human AhR around the phosphorylation site of Serine 36
- 亚型
- IgG
- Top Product
- Discover our top product AHR Primary Antibody
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- 应用备注
- WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- Aryl Hydrocarbon Receptor (AHR)
- 别名
- AhR (AHR 产品)
- 别名
- AHR antibody, ahr1 antibody, ahr antibody, bHLHe76 antibody, Ah antibody, Ahh antibody, Ahre antibody, In antibody, aryl hydrocarbon receptor S homeolog antibody, aryl hydrocarbon receptor antibody, aryl-hydrocarbon receptor antibody, ahr.S antibody, AHR antibody, ahr antibody, Ahr antibody
- 背景
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Description: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
Gene: AHR
- 分子量
- 90kDa
- 基因ID
- 196
- UniProt
- P35869, A9YTQ3
- 途径
- Regulation of Cell Size
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