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GATA4 抗体 (pSer105)

GATA4 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of GATA4 phosphorylation expression in HepG2 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. (GATA4 抗体 (pSer105))

ABIN6267526 at 1/200 staining Human pancreas tissue sections by IHC-P. (GATA4 抗体 (pSer105))

ABIN6267526 staining HepG2 cells by ICC/IF. (GATA4 抗体 (pSer105))

ABIN6267526 at 1/200 staining Human pancreas tissue sections by IHC-P. (GATA4 抗体 (pSer105))

ABIN6267526 at 1/200 staining Mouse testis tissue sections by IHC-P. (GATA4 抗体 (pSer105))

ABIN6267526 at 1/200 staining Mouse lung tissue sections by IHC-P. (GATA4 抗体 (pSer105))

Western blot analysis of Phospho-GATA4 (Ser105) expression in various lysates (GATA4 抗体 (pSer105))

ABIN6267526 at 1/200 staining Mouse testis tissue sections by IHC-P. (GATA4 抗体 (pSer105))

ABIN6267526 staining 293 by IF/ICC. (GATA4 抗体 (pSer105))

ABIN6267526 at 1/200 staining Mouse brain tissue sections by IHC-P. (GATA4 抗体 (pSer105))

ABIN6267526 at 1/200 staining Mouse lung tissue sections by IHC-P. (GATA4 抗体 (pSer105))

11 images

产品编号 ABIN6256094

发货至: 中国

Datasheet as PDF

抗原 See all GATA4 抗体

GATA4 (GATA Binding Protein 4 (GATA4))
抗原表位
15

12

11

5

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer105
适用
89

64

62

6

4

2

1

1

1

1
人, 大鼠, 小鼠
宿主
80

9

1
兔
Compatible Secondaries
克隆类型
72

18
多克隆
标记
55

4

3

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1
This GATA4 antibody is un-conjugated
应用范围
65

30

21

18

13

13

12

5

5

2

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

Phospho-GATA4 (Ser105) Antibody detects endogenous levels of GATA4 only when phosphorylated at Serine 105.

预测反应

Pig,Bovine,Rabbit,Dog,Chicken,Xenopus

纯化方法

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

免疫原

A synthesized peptide derived from human GATA4 around the phosphorylation site of Ser105.

亚型

IgG

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anti-GATA Binding Protein 4 (GATA4) (pSer262) antibody
GATA4 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 4 (GATA4) antibody
GATA4 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-GATA Binding Protein 4 (GATA4) (AA 228-440) antibody
GATA4 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 4 (GATA4) (AA 50-150) antibody
GATA4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 4 (GATA4) (AA 261-360) antibody
GATA4 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 4 (GATA4) (AA 201-442) antibody
GATA4 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 4 (GATA4) (AA 330-380) antibody
GATA4 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 4 (GATA4) (AA 343-442) antibody
GATA4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6C6 unconjugated

anti-GATA Binding Protein 4 (GATA4) (AA 296-442) antibody
GATA4 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1H8 unconjugated

anti-GATA Binding Protein 4 (GATA4) antibody
GATA4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6H10 unconjugated

应用备注

WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

GATA4 (GATA Binding Protein 4 (GATA4))

别名

GATA4 (GATA4 产品)

别名

gata-4 antibody, xgata4 antibody, xGATA-4 antibody, MGC81427 antibody, GATA4 antibody, GATA-4 antibody, Gata4 antibody, gata4 antibody, ASD2 antibody, VSD1 antibody, Gata-4 antibody, gata antibody, GATA binding protein 4 antibody, GATA binding protein 4 L homeolog antibody, glutamyl-tRNA(Gln) amidotransferase subunit A antibody, gata4 transcription factor antibody, GATA binding protein 4 S homeolog antibody, GATA4 antibody, gata4.L antibody, gata4 antibody, gatA4 antibody, Gata4 antibody, gata4.S antibody

背景

Description: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function (PubMed:24000169, PubMed:27984724). In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression (PubMed:27984724). Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (By similarity). Promotes cardiac myocyte enlargement (PubMed:20081228). Required during testicular development (PubMed:21220346). May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase (PubMed:15734735).
Gene: GATA4

分子量

44kDa

基因ID

2626

UniProt

P43694

途径

Peptide Hormone Metabolism, Carbohydrate Homeostasis

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