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ESR2 抗体 (pSer105)

ESR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6256093
发货至: 中国
  • 抗原 See all ESR2 抗体
    ESR2 (Estrogen Receptor 2 (ESR2))
    抗原表位
    • 27
    • 24
    • 16
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    • 12
    • 8
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    pSer105
    适用
    • 192
    • 108
    • 91
    • 32
    • 19
    • 15
    • 15
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    人, 小鼠, 大鼠
    宿主
    • 170
    • 35
    • 1
    • 1
    克隆类型
    • 164
    • 43
    多克隆
    标记
    • 90
    • 17
    • 15
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    • 5
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    This ESR2 antibody is un-conjugated
    应用范围
    • 168
    • 72
    • 55
    • 36
    • 36
    • 26
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    • 17
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    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Phospho-Estrogen Receptor-beta (Ser105) Antibody detects endogenous levels of Estrogen Receptor-beta only when phosphorylated at Serine 105.
    预测反应
    Horse,Sheep,Dog,Chicken
    纯化方法
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    免疫原
    A synthesized peptide derived from human Estrogen Receptor- beta around the phosphorylation site of Ser105.
    亚型
    IgG
    Top Product
    Discover our top product ESR2 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    ESR2 (Estrogen Receptor 2 (ESR2))
    别名
    ESR2 (ESR2 产品)
    别名
    ER-BETA antibody, ESR-BETA antibody, ESRB antibody, ESTRB antibody, Erb antibody, NR3A2 antibody, ER[b]1 antibody, zfER-beta1 antibody, zfER[b]1 antibody, erb2 antibody, CERB antibody, ERB antibody, erb antibody, esrb antibody, estrb antibody, nr3a2 antibody, ERbeta antibody, er-beta antibody, esr-beta antibody, ESR2 antibody, ERBETA antibody, er antibody, ER-beta antibody, ER[b] antibody, Estrb antibody, ER[b]2 antibody, ER[b]a antibody, zfER[b]2 antibody, zfER-beta2 antibody, Erb2 antibody, esr2 antibody, erbeta antibody, Esr2 antibody, ERBeta2 antibody, estrogen receptor 2 antibody, estrogen receptor 2b antibody, estrogen receptor beta 2 antibody, estrogen receptor 2 (beta) antibody, estrogen receptor 2a antibody, estrogen receptor beta antibody, ESR2 antibody, esr2b antibody, erb2 antibody, esr2 antibody, Esr2 antibody, esr2a antibody, erbeta antibody
    背景

    Description: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner (PubMed:20074560). Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.

    Gene: ESR2

    分子量
    59kDa
    基因ID
    2100
    UniProt
    Q92731
    途径
    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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