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SHP1 抗体 (pTyr536)

PTPN6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6255949
发货至: 中国
  • 抗原 See all SHP1 (PTPN6) 抗体
    SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
    抗原表位
    • 34
    • 12
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
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    • 2
    • 1
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    • 1
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    pTyr536
    适用
    • 116
    • 71
    • 53
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 106
    • 12
    • 1
    克隆类型
    • 100
    • 19
    多克隆
    标记
    • 54
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This SHP1 antibody is un-conjugated
    应用范围
    • 80
    • 30
    • 22
    • 19
    • 18
    • 14
    • 14
    • 10
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Phospho-SHP1 (Tyr536) Antibody detects endogenous levels of SHP1 only when phosphorylated at Tyrosine 536.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    免疫原
    A synthesized peptide derived from human SHP1 around the phosphorylation site of Tyr536.
    亚型
    IgG
    Top Product
    Discover our top product PTPN6 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
    别名
    PTPN6 (PTPN6 产品)
    别名
    HCPH antibody, HPTP1C antibody, PTP-1C antibody, SH-PTP1 antibody, SHP-1 antibody, SHP-1L antibody, SHP1 antibody, DRPLA antibody, Hcph antibody, Ptp1C antibody, me antibody, motheaten antibody, Ptph6 antibody, Shp-1 antibody, fj22f05 antibody, wu:fj22f05 antibody, zgc:55501 antibody, ptpn6 antibody, protein tyrosine phosphatase, non-receptor type 6 antibody, protein tyrosine phosphatase, non-receptor type 6 L homeolog antibody, PTPN6 antibody, Ptpn6 antibody, ptpn6 antibody, ptpn6.L antibody
    背景

    Description: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.

    Gene: PTPN6

    分子量
    67kDa
    基因ID
    5777
    UniProt
    P29350
    途径
    JAK/STAT Signaling, TCR Signaling, TLR signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling
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