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FRS2 抗体 (pTyr436)

FRS2 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6255918
发货至: 中国
  • 抗原 See all FRS2 抗体
    FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
    抗原表位
    • 15
    • 13
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr436
    适用
    • 61
    • 24
    • 19
    • 2
    人, 小鼠
    宿主
    • 71
    • 6
    • 2
    • 1
    克隆类型
    • 77
    • 3
    多克隆
    标记
    • 37
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FRS2 antibody is un-conjugated
    应用范围
    • 57
    • 41
    • 14
    • 14
    • 12
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    Phospho-FRS2 (Tyr436) Antibody detects endogenous levels of FRS2 only when phosphorylated at Tyrosine 436.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    免疫原
    A synthesized peptide derived from human FRS2 around the phosphorylation site of Tyr436.
    亚型
    IgG
    Top Product
    Discover our top product FRS2 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
    别名
    FRS2 (FRS2 产品)
    别名
    frs2 antibody, wu:fd21h10 antibody, zgc:91973 antibody, FRS2A antibody, FRS2alpha antibody, SNT antibody, SNT-1 antibody, SNT1 antibody, 4732458E18 antibody, C330018A15Rik antibody, Frs2alpha antibody, fibroblast growth factor receptor substrate 2 antibody, fibroblast growth factor receptor substrate 2b antibody, FRS2 antibody, frs2b antibody, Frs2 antibody
    背景

    Description: Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

    Gene: FRS2

    分子量
    65kDa
    基因ID
    10818
    UniProt
    Q8WU20
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Signaling Events mediated by VEGFR1 and VEGFR2
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