CaMK2 alpha/beta/delta 抗体 (pThr305)
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- 抗原 See all CaMK2 alpha/beta/delta products
- CaMK2 alpha/beta/delta
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抗原表位
- pThr305
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CaMK2 alpha/beta/delta antibody is un-conjugated
- 应用范围
- Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- Phospho-CaMK2 alpha/ beta/ delta (Thr305) Antibody detects endogenous levels of CaMK2 alpha/ beta/ delta only when phosphorylated at Threonine 305
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- 免疫原
- A synthesized peptide derived from human CaMK2 alpha/ beta/ delta around the phosphorylation site of Threonine 305
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- CaMK2 alpha/beta/delta
- 别名
- CaMK2 alpha/ beta/ delta (CaMK2 alpha/beta/delta 产品)
- 背景
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Description: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).
Gene: CAMK2A
- 分子量
- 54kDa
- 基因ID
- 815
- UniProt
- Q9UQM7, Q13554, Q13557
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