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CaMK2 alpha/beta/delta 抗体 (pThr305)

适用: 人, 小鼠, 大鼠 IHC, ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6255659
发货至: 中国
  • 抗原 See all CaMK2 alpha/beta/delta products
    CaMK2 alpha/beta/delta
    抗原表位
    • 2
    • 2
    • 1
    pThr305
    适用
    人, 小鼠, 大鼠
    宿主
    • 3
    克隆类型
    • 3
    多克隆
    标记
    • 3
    This CaMK2 alpha/beta/delta antibody is un-conjugated
    应用范围
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Phospho-CaMK2 alpha/ beta/ delta (Thr305) Antibody detects endogenous levels of CaMK2 alpha/ beta/ delta only when phosphorylated at Threonine 305
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    免疫原
    A synthesized peptide derived from human CaMK2 alpha/ beta/ delta around the phosphorylation site of Threonine 305
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    CaMK2 alpha/beta/delta
    别名
    CaMK2 alpha/ beta/ delta (CaMK2 alpha/beta/delta 产品)
    背景

    Description: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).

    Gene: CAMK2A

    分子量
    54kDa
    基因ID
    815
    UniProt
    Q9UQM7, Q13554, Q13557
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