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EIF2S1 抗体 (pSer51)

EIF2S1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

MCF-7 and MDA-MB-231 cells were treated with the indicated concentrations of BA for 24 h, and the protein levels of ER stress-associated signals were stimulated by BA in a dose-dependent manner, including GRP78, p-PERK/PERK, p-eIF2α/eIF2α, CHOP, and caspase-12. (EIF2S1 抗体 (pSer51))

ABIN6267301 at 1/100 staining mouse kidney tissue sections by IHC-P. (EIF2S1 抗体 (pSer51))

ABIN6267301 at 1/100 staining human placenta tissue sections by IHC-P. (EIF2S1 抗体 (pSer51))

ABIN6267301 at 1/100 staining human appendiceal tissue sections by IHC-P. (EIF2S1 抗体 (pSer51))

ABIN6267301 at 1/100 staining rat uterine tissue sections by IHC-P. (EIF2S1 抗体 (pSer51))

ABIN6267301 at 1/100 staining rat ovarian tissue sections by IHC-P. (EIF2S1 抗体 (pSer51))

ABIN6267301 staining K562 by IF/ICC. (EIF2S1 抗体 (pSer51))

Western blot analysis of Phospho-eIF2 alpha (Ser51) expression in various lysates (EIF2S1 抗体 (pSer51))

ABIN6267301 at 1/100 staining human lung tissue sections by IHC-P. (EIF2S1 抗体 (pSer51))

ABIN6267301 at 1/100 staining mouse gastric tissue sections by IHC-P. (EIF2S1 抗体 (pSer51))

Western blot analysis of eIF2 alpha phosphorylation expression in IFN-α treated K562 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. (EIF2S1 抗体 (pSer51))

ABIN6267301 at 1/100 staining rat kidney tissue sections by IHC-P. (EIF2S1 抗体 (pSer51))

ABIN6267301 at 1/100 staining mouse lung tissue sections by IHC-P. (EIF2S1 抗体 (pSer51))

13 images

(2 references)

产品编号 ABIN6255389

发货至: 中国

Datasheet as PDF

抗原 See all EIF2S1 抗体

EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
抗原表位
18

10

8

5

5

5

5

4

2

1

1

1

1

1

1

1

1

1

1
pSer51
适用
72

42

32

10

8

8

7

6

6

6

5

5

4

3

2

2

1

1

1
人, 大鼠, 小鼠
宿主
73

14

2
兔
Compatible Secondaries
克隆类型
71

18
多克隆
标记
55

5

4

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This EIF2S1 antibody is un-conjugated
应用范围
60

39

32

28

17

13

13

10

7

6

3

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

Phospho-eIF2 alpha (Ser51) Antibody detects endogenous levels of eIF2 alpha only when phosphorylated at Ser52, which site historically referenced as Ser51.

预测反应

Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

纯化方法

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

免疫原

A synthesized peptide derived from human eIF2 alpha around the phosphorylation site of Ser51.

亚型

IgG

Top Product

Discover our top product EIF2S1 Primary Antibody
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (AA 1-315) antibody
EIF2S1 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 3H12-C11 unconjugated

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) antibody
EIF2S1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5A5 unconjugated

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (N-Term) antibody
EIF2S1 适用: 人, 大鼠, 小鼠, Pig WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer51) antibody
EIF2S1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 1C6 unconjugated Recombinant Antibody

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer49) antibody
EIF2S1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer51) antibody
EIF2S1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) antibody
EIF2S1 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) antibody
EIF2S1 适用: 人, 大鼠, 犬, 猴 WB, FACS 宿主: 小鼠 Monoclonal 3H7 unconjugated

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (AA 276-315) antibody
EIF2S1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (C-Term) antibody
EIF2S1 适用: 人, 大鼠, 小鼠, Cow, 犬, 斑马鱼, Pig, 猴, 兔, 豚鼠, 小鸡, 马, 山羊, Bat, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:500, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
Cai, Zheng, Gu, Wang, Wang, Yang, Zhang, Wang, Fu, Wang: "Betulinic acid chemosensitizes breast cancer by triggering ER stress-mediated apoptosis by directly targeting GRP78." in: Cell death & disease, Vol. 9, Issue 6, pp. 636, (2018) (PubMed).

Liu, Shen, Wang, Liu, Zheng, Luo: "EndophilinA2 protects against angiotensin II-induced cardiac hypertrophy by inhibiting angiotensin II type 1 receptor trafficking in neonatal rat cardiomyocytes." in: Journal of cellular biochemistry, (2018) (PubMed).
抗原

EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

别名

EIF2S1 (EIF2S1 产品)

别名

EIF-2 antibody, EIF-2A antibody, EIF-2alpha antibody, EIF2 antibody, EIF2A antibody, Eif2s1 antibody, eif2s1l antibody, fb36a08 antibody, wu:fb36a08 antibody, zgc:56510 antibody, 0910001O23Rik antibody, 2410026C18Rik antibody, 35kDa antibody, Eif2a antibody, eIF2alpha antibody, eif2a antibody, CG9946 antibody, Dmel\\CG9946 antibody, Eif2alpha antibody, IF2A_DROME antibody, M(1)14C antibody, M(1)19-153 antibody, M(1)8e3-10 antibody, deIF2alpha antibody, eIF-2 antibody, eIF-2 a antibody, eIF-2 alpha antibody, eIF2 alpha antibody, eIF2-alpha antibody, eIF2a antibody, eiF-2alpha antibody, elF2alpha antibody, l(1)14Cf antibody, l(1)19-153 antibody, eukaryotic translation initiation factor 2 subunit alpha antibody, eukaryotic translation initiation factor 2, subunit 1 alpha a antibody, eukaryotic translation initiation factor 2, subunit 1 alpha antibody, eukaryotic translation initiation factor 2 alpha subunit antibody, Eukaryotic translation initiation factor 2 subunit 1 antibody, eukaryotic translation initiation factor 2 subunit alpha L homeolog antibody, eukaryotic translation Initiation Factor 2alpha antibody, EIF2S1 antibody, eif2s1a antibody, Eif2s1 antibody, eif2s1 antibody, LOC693063 antibody, CNI00230 antibody, THAPSDRAFT_105 antibody, if2a antibody, eif2s1.L antibody, eIF-2alpha antibody

背景

Description: Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Gene: EIF2S1

分子量

38kDa

基因ID

1965

UniProt

P05198

途径

Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C

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