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FOXO3 抗体 (pSer253)

FOXO3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of FKHRL1 phosphorylation expression in serum treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. (FOXO3 抗体 (pSer253))

ABIN6267237 at 1/100 staining mouse brain tissue sections by IHC-P. (FOXO3 抗体 (pSer253))

ABIN6267237 at 1/100 staining human appendiceal tissue sections by IHC-P. (FOXO3 抗体 (pSer253))

ABIN6267237 at 1/100 staining mouse kidney tissue sections by IHC-P. (FOXO3 抗体 (pSer253))

ABIN6267237 at 1/100 staining rat gastric tissue sections by IHC-P. (FOXO3 抗体 (pSer253))

Western blot analysis of Phospho-FKHRL1 (Ser253) expression in various lysates (FOXO3 抗体 (pSer253))

ABIN6267237 at 1/100 staining human skin tissue sections by IHC-P. (FOXO3 抗体 (pSer253))

ABIN6267237 at 1/100 staining human TB tissue sections by IHC-P. (FOXO3 抗体 (pSer253))

ABIN6267237 at 1/100 staining mouse spleen tissue sections by IHC-P. (FOXO3 抗体 (pSer253))

ABIN6267237 at 1/100 staining rat uterine tissue sections by IHC-P. (FOXO3 抗体 (pSer253))

ABIN6267237 at 1/100 staining human liver tissue sections by IHC-P. (FOXO3 抗体 (pSer253))

ABIN6267237 at 1/100 staining rat spleen tissue sections by IHC-P. (FOXO3 抗体 (pSer253))

12 images

(1 reference)

产品编号 ABIN6255131

发货至: 中国

Datasheet as PDF

抗原 See all FOXO3 抗体

FOXO3 (Forkhead Box O3 (FOXO3))
抗原表位
33

13

9

8

8

8

8

7

7

7

7

7

7

6

6

5

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer253
适用
165

114

105

10

8

6

5

5

5

4

4

3

3

2

2

1
人, 小鼠, 大鼠
宿主
161

5

1

1
兔
Compatible Secondaries
克隆类型
153

15
多克隆
标记
69

14

9

9

9

9

9

9

6

5

5

4

1

1

1

1

1

1

1

1

1

1

1
This FOXO3 antibody is un-conjugated
应用范围
97

59

51

31

23

15

15

14

14

12

5

3

2

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

Phospho-FOXO3A (Ser253) Antibody detects endogenous levels of FOXO3A only when phosphorylated at Serine 253.

预测反应

Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

纯化方法

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

免疫原

A synthesized peptide derived from human FOXO3A around the phosphorylation site of Ser253.

亚型

IgG
anti-Forkhead Box O3 (FOXO3) (AA 394-672) antibody
FOXO3 适用: 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) (C-Term) antibody
Verified FOXO3 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) (pSer318), (pSer321) antibody
FOXO3 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) (C-Term) antibody
KO Validated FOXO3 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) (N-Term) antibody
FOXO3 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 绵羊, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) antibody
FOXO3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 1E2 unconjugated Recombinant Antibody

anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibody
FOXO3 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1F6 unconjugated

anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibody
FOXO3 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E11 unconjugated

anti-Forkhead Box O3 (FOXO3) (N-Term) antibody
FOXO3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) (pSer425) antibody
FOXO3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
Yang, Lv, Chen, Wang, Liu, Shi, Liu, Wang: "The effect of vitamin D on sarcopenia depends on the level of physical activity in older adults." in: Journal of cachexia, sarcopenia and muscle, Vol. 11, Issue 3, pp. 678-689, (2021) (PubMed).
抗原

FOXO3 (Forkhead Box O3 (FOXO3))

别名

FOXO3 (FOXO3 产品)

别名

AF6q21 antibody, FKHRL1 antibody, FKHRL1P2 antibody, FOXO2 antibody, FOXO3A antibody, zgc:92176 antibody, wu:fb50g02 antibody, wu:fi33f07 antibody, Fkhrl1 antibody, Foxo3a antibody, FoxO3A antibody, 1110048B16Rik antibody, 2010203A17Rik antibody, C76856 antibody, Fkhr2 antibody, FOXO-3 antibody, FOXO3 antibody, foxo3a antibody, xfoxo3 antibody, foxO3 antibody, foxO antibody, fkhr antibody, foxo5 antibody, wu:fj65a12 antibody, zFkhr antibody, forkhead box O3 antibody, forkhead box O3A antibody, forkhead box O3 L homeolog antibody, forkhead box O3b antibody, FOXO3 antibody, foxo3a antibody, Foxo3 antibody, foxo3.L antibody, foxo3 antibody, foxO3 antibody, foxo3b antibody

背景

Description: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress (PubMed:10102273, PubMed:16751106). Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3' (PubMed:21329882). Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation (PubMed:21329882). In response to metabolic stress, translocates into the mitochondria where it promotes mtDNA transcription (PubMed:23283301).
Gene: FOXO3

分子量

97kDa

基因ID

2309

UniProt

O43524

途径

Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis

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