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FMR1 抗体 (pSer499)

FMR1 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6254033
发货至: 中国
  • 抗原 See all FMR1 抗体
    FMR1 (Fragile X Mental Retardation 1 (FMR1))
    抗原表位
    • 15
    • 8
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer499
    适用
    • 73
    • 53
    • 41
    • 15
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 57
    • 18
    • 2
    克隆类型
    • 52
    • 25
    多克隆
    标记
    • 44
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FMR1 antibody is un-conjugated
    应用范围
    • 63
    • 25
    • 18
    • 15
    • 14
    • 13
    • 10
    • 7
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    小鼠, 大鼠
    预测反应
    bovine, canine, chicken, human, mouse, non-human primates, sheep, Xenopus, zebra fish
    纯化方法
    Antigen Affinity Purified from Pooled Serum
    免疫原
    Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser499 conjugated to KLH
    Top Product
    Discover our top product FMR1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
    储存条件
    -20 °C
  • Bartley, OKeefe, Blice-Baum, Mihailescu, Gong, Miyares, Karaca, Bordey: "Mammalian FMRP S499 Is Phosphorylated by CK2 and Promotes Secondary Phosphorylation of FMRP." in: eNeuro, Vol. 3, Issue 6, (2017) (PubMed).

    Reynolds, Smith, Jefferson, Lugo: "Comparison of Equivalence between Two Commercially Available S499-Phosphorylated FMRP Antibodies in Mice." in: PLoS ONE, Vol. 10, Issue 11, pp. e0143134, (2016) (PubMed).

    Guimarães-Souza, Perche, Morgans, Duvoisin, Calaza: "Fragile X Mental Retardation Protein expression in the retina is regulated by light." in: Experimental eye research, Vol. 146, pp. 72-82, (2016) (PubMed).

    Bartley, OKeefe, Bordey: "FMRP S499 is phosphorylated independent of mTORC1-S6K1 activity." in: PLoS ONE, Vol. 9, Issue 5, pp. e96956, (2015) (PubMed).

  • 抗原
    FMR1 (Fragile X Mental Retardation 1 (FMR1))
    别名
    FMR1 (FMR1 产品)
    分子量
    '71 kDa
    基因ID
    24948
    UniProt
    Q80WE1
    途径
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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