Ku70 + Ku80 抗体
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- 抗原 See all Ku70 + Ku80 (KU80) products
- Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))
- 适用
- 人, 灵长类
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Ku70 + Ku80 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Does not react with mouse, rat, chicken
- 纯化方法
- Protein G purified monoclonal antibody
- 免疫原
- Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.
- 克隆位点
- KU729
- 亚型
- IgG1 kappa
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anti-CG18801 Gene Product From Transcript CG18801-RA (KU80) antibody (PE)
KU80 适用: 人, 灵长类 FACS, IF 宿主: 小鼠 Monoclonal KU729 PE
anti-CG18801 Gene Product From Transcript CG18801-RA (KU80) antibodyKU80 适用: 人, 灵长类 FACS, IF, ICC 宿主: 小鼠 Monoclonal KU729 unconjugated
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- 应用备注
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Flow cytometry: 0.5-1 μg/10e6 cells
IF: 0.5-1.0 μg/mL
Immunocytochemistry (Acetone-fixed cells): 0.25-0.5 μg/mL for 30 minutes at RT
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Ku70 + Ku80 antibody to be titered up or down for optimal performance. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.2 mg/mL
- 缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- 抗原
- Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))
- 别名
- Ku70 + Ku80 (KU80 产品)
- 背景
- This antibody recognizes a dimer of two proteins of 70 kDa (Ku70) and ~80 kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
- 基因ID
- 2547
- UniProt
- Q6FG89
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