EZH2 抗体 (AA 410-440)
(4 references)-
- 抗原 See all EZH2 抗体
- EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
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抗原表位
- AA 410-440
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EZH2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- X, Pr
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This EZH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from 410-440aa of human EZH2.
- 克隆位点
- RB2921
- 亚型
- IgG
- Top Product
- Discover our top product EZH2 Primary Antibody
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anti-Enhancer of Zeste Homolog 2 (EZH2) (AA 51-285) antibody
EZH2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Enhancer of Zeste Homolog 2 (EZH2) (AA 1-194) antibodyEZH2 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6G4F4 unconjugated
anti-Enhancer of Zeste Homolog 2 (EZH2) (AA 1-296), (N-Term) antibodyEZH2 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB23144 unconjugated
anti-Enhancer of Zeste Homolog 2 (EZH2) antibodyEZH2 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 144CT2-1-1-5 unconjugated
anti-Enhancer of Zeste Homolog 2 (EZH2) (AA 1-250) antibodyEZH2 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Enhancer of Zeste Homolog 2 (EZH2) antibodyEZH2 适用: 人, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Enhancer of Zeste Homolog 2 (EZH2) antibodyEZH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Enhancer of Zeste Homolog 2 (EZH2) antibodyEZH2 适用: 人 WB 宿主: 小鼠 Monoclonal EZH2-2536 unconjugated
anti-Enhancer of Zeste Homolog 2 (EZH2) (AA 1-250) antibodyEZH2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Enhancer of Zeste Homolog 2 (EZH2) (AA 1-110) antibodyEZH2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C3 unconjugated
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- 应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "STAT3 signaling drives EZH2 transcriptional activation and mediates poor prognosis in gastric cancer." in: Molecular cancer, Vol. 15, Issue 1, pp. 79, (2017) (PubMed).
: "MicroRNA-144 suppresses tumorigenesis and tumor progression of astrocytoma by targeting EZH2." in: Human pathology, Vol. 46, Issue 7, pp. 971-80, (2015) (PubMed).
: "Inhibition of enhancer of zeste homolog 2 (EZH2) expression is associated with decreased tumor cell proliferation, migration, and invasion in endometrial cancer cell lines." in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Vol. 23, Issue 6, pp. 997-1005, (2014) (PubMed).
: "Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer." in: Cancer research, Vol. 66, Issue 16, pp. 7889-98, (2007) (PubMed).
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: "STAT3 signaling drives EZH2 transcriptional activation and mediates poor prognosis in gastric cancer." in: Molecular cancer, Vol. 15, Issue 1, pp. 79, (2017) (PubMed).
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- 抗原
- EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
- 别名
- EZH2 (EZH2 产品)
- 别名
- ENX-1 antibody, ENX1 antibody, EZH1 antibody, EZH2b antibody, KMT6 antibody, KMT6A antibody, WVS antibody, WVS2 antibody, eya2 antibody, im:7149338 antibody, zgc:136376 antibody, zgc:152758 antibody, EZH2 antibody, enx-1 antibody, enx1 antibody, ezh1 antibody, kmt6 antibody, xez antibody, Enx-1 antibody, Enx1h antibody, mKIAA4065 antibody, ezh2 antibody, olezh2 antibody, enhancer of zeste 2 polycomb repressive complex 2 subunit antibody, enhancer of zeste 2 polycomb repressive complex 2 subunit L homeolog antibody, enhancer of zeste 2 polycomb repressive complex 2 subunit S homeolog antibody, EZH2 antibody, ezh2 antibody, Ezh2 antibody, ezh2.L antibody, ezh2.S antibody
- 背景
- EZH2, SUZ12, and EED form a complex that methylates nucleosomal histone H3 at Lys27. EZH2 contains a SET domain, a signature motif for all known histone lysine methyltransferases except the H3-K79 methyltransferase DOT1, and is therefore likely to be the catalytic subunit. Consequently, EZH2 is thought to regulate gene expression by controlling chromatin structure. Several lines of evidence suggested a critical role for the EZH2 protein during normal and perturbed development of the hematopoietic and central nervous systems. The EZH2 protein has been shown to associate with the VAV1 protooncoprotein and with the XNP protein, the product of a gene associated with mental retardation. Additionally, due to mapping of EZH2 to the 7q35-q36 chromosomal region associated with myeloid disorders, this protein is suggested to participate in the genetic events triggering myeloid leukemia.
- 分子量
- 85363
- NCBI登录号
- NP_001190176, NP_001190177, NP_001190178, NP_004447, NP_694543
- UniProt
- Q15910
- 途径
- Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation
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